Mechanisms and time course of impaired skeletal muscle glucose transport activity in streptozocin diabetic rats.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Islet transplantation under the kidney capsule fully corrects the impaired skeletal muscle glucose transport system of streptozocin diabetic rats.

Chronic insulin therapy improves but does not restore impaired insulin-mediated muscle glucose uptake in human diabetes or muscle glucose uptake, transport, and transporter translocation in streptozocin diabetic rats. To determine whether this inability is due to inadequate insulin replacement, we studied fasted streptozocin-induced diabetic Lewis rats either untreated or after islet transplant...

متن کامل

Fumaria parviflora Lam. Effect on Serum Levels of Glucose and Lipids in Streptozocin- Induced Diabetic Rats

Background and Objective: Lowering serum glucose and lipid levels in diabetic patients by using natural materials is of great importance. In this study, the effect of oral consumption of Fumaria Parviflora Lamwas was assessed on serum glucose and lipid levels in streptozocin diabetic rats. Materials and Methods: In this experimental study, 32 male Wistar rats were divided into four groups of co...

متن کامل

Effect of resveratrol on SNARE proteins expression and insulin resistance in skeletal muscle of diabetic rats

Objective(s): Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex proteins are involved in membrane trafficking. The expression of isoforms of SNAP-23, syntaxin-4, and VAMP-2 is significantly done in skeletal muscles; they control GLUT4 trafficking. It is believed that type 2 diabetes could be caused by the modifications in the express...

متن کامل

Hypoglycemic Activity of Inflorescence of Borassus flabellifer Extracts on Blood Glucose Levels of Streptozocin-Induced Diabetic Rats

Evaluation of hypoglycemic activity of inflorescence of Borassus flabellifer extract in male wistar rats has been investigated. Antidiabetic potentials were studies by the orally administration of plant extract at the doses of 150, 300 and 600 mg/kg in streptozocin-induced diabetic male wistar rats. Treatment of streptozocin-induced diabetic male wistar rats with the extracts caused a signifi...

متن کامل

Regulates Glucose Transport in Skeletal Muscle TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle Running Head: TBC1D1 Regulates Glucose Transport in Skeletal Muscle

This is an uncopyedited electronic version of an article accepted for publication in Diabetes. The American Diabetes Association, publisher of Diabetes, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisher-authenticated version will be available in a future issue of Diabetes in print and online...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1995

ISSN: 0021-9738

DOI: 10.1172/jci118053